File Python Hashlib
import hashlib
BLOCKSIZE = 65536
hasher = hashlib.md5()
with open('anotherfile.txt', 'rb') as afile:
buf = afile.read(BLOCKSIZE)
while len(buf) > 0:
hasher.update(buf)
buf = afile.read(BLOCKSIZE)
print(hasher.hexdigest())
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